function of nucleic acids in the differentiation of neoplastic processes
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function of nucleic acids in the differentiation of neoplastic processes

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Published by Israel Program for Scientific Translations in Jerusalem .
Written in English


  • Cancer.,
  • Nucleic acids.,
  • Embryology.

Book details:

Edition Notes

Statement[by] Ya. G. Erenpreis. [Translated by Y. S. Halpern]
LC ClassificationsRC269 .E713
The Physical Object
Paginationiv, 148 p.
Number of Pages148
ID Numbers
Open LibraryOL5934501M
LC Control Number65000879

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The primary function of nucleic acids, which in nature include DNA and RNA, is to store and transfer genetic information. RNA is also essential for protein synthesis. Nucleic acids consist of nucleotides, which in turn are composed of a sugar, a phosphate group and a nitrogenous base. The nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are the molecular repositories for genetic information. The structure of every protein, and ultimately of every cell constituent, is a product of information programmed into the nucleotide sequence of a cell's nucleic acids. Nucleic acids were named based partly on their chemical properties and partly on the observation that they represented a major constituent of the cell nucleus. That nucleic acids form the chemical basis for the transmission of genetic traits was not realized until about 50 years ago (1). Prior to that time, there was considerable disagreement Author: William B. Coleman. Receptors of the innate immune system recognize conserved microbial features and provide key signals that initiate immune responses. Multiple transmembrane and cytosolic receptors have evolved to recognize RNA and DNA, including members of the Toll-like receptor and RIG-I-like receptor families and several DNA sensors. This strategy enables recognition of a broad range of pathogens; however Cited by:

An Overview of Nucleic Acid Chemistry, Structure, and Function E. Structure and function of nucleic acids as cell con- that are associated with the process of neoplastic transformation and. This chapter discusses the nucleic acids of normal tissues and tumors. Neoplastic tissues are frequently abnormal in regard to enzyme content and metabolism and with respect to the number and structure of the chromosomes. Abstract. Many antimicrobial substances, both synthetic chemicals and natural products, directly inhibit the biosynthesis of nucleic acids. However, very few of these inhibitors are clinically useful as antimicrobial drugs because most of them do not distinguish between nucleic acid synthesis by the infecting micro-organism and that by the : T. J. Franklin, G. A. Snow. Ultimately, one wishes to determine how genes—and the proteins they encode—function in the intact organism. Although it may sound counterintuitive, one of the most direct ways to find out what a gene does is to see what happens to the organism when that gene is missing. Studying mutant organisms that have acquired changes or deletions in their nucleotide sequences is a time-honored Cited by:

  Nucleic acids were first isolated from the cellular nucleus, hence the name. Nucleic acids are macromolecules, huge polymers with molecular masses of over million. 4. FUNCTION OF NUCLEIC ACIDS: Functions of DNA (deoxyribonucleic acid): DNA is a permanent storage place for genetic information. There are two types of nucleic acids: DNA (deoxyribonucleic acid), and RNA (ribonucleic acid). The main function of the nucleic acids is to transmit genetic material or information from parent cell to the daughter cells or from one generation to the next. The most common form of genetic material is DNA. Nucleic acids are tiny bits of matter with large roles to play. Named for their location -- the nucleus -- these acids carry information that help cells make proteins and replicate their genetic information exactly. Nucleic acid was first identified during the winter of – In Supplementary Table 1 we provide a detailed list of human DRBPs, with comments on their nucleic acid binding properties, structure, and function. These proteins, drawn form the proteins mentioned above, were selected based on experimental evidence demonstrating their ability to bind directly to both DNA and RNA, generally obtained Cited by: